Efficacy observation of intranasal drainage for esophageal cancer anastomotic fistula with abscess in thoracic cavity or mediastinum
10.3760/cma.j.cn115355-20240703-00325
- VernacularTitle:经鼻内引流治疗食管癌术后吻合口瘘伴胸腔或纵隔脓肿效果观察
- Author:
Shengzu PENG
1
;
Bin WANG
;
Kai ZHANG
;
Hui YE
;
Bin YANG
Author Information
1. 山西省肿瘤医院 中国医学科学院肿瘤医院山西医院 山西医科大学附属肿瘤医院胸外科，太原 030013
- Keywords:
Esophageal neoplasms;
Anastomotic fistula;
Thoracic abscess;
Mediastinal abscess;
Internal drainage
- From:
Cancer Research and Clinic
2024;36(11):843-846
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical effect of intranasal drainage in treatment of anastomotic fistula accompanied with abscess in thoracic cavity or mediastinum after esophageal cancer surgery.Methods:A retrospective case cohort study was conducted. The clinical data of 32 patients with anastomotic fistula and abscess in thoracic cavity or mediastinum after esophageal cancer surgery in Shanxi Province Cancer Hospital from January 2017 to December 2022 were analyzed. Among them, 15 cases were treated with traditional closed thoracic drainage (the traditional group), and 17 cases were treated with intranasal drainage (the intranasal drainage group). The time of abnormal body temperature, antibiotic usage time, anastomotic fistula healing time, hospitalization stay and the incidence of anastomotic stenosis were compared between the both groups.Results:There were no statistically significant differences in age, gender, tumor staging, surgical method, and fistula diameter between the 2 groups (all P>0.05). The time of abnormal body temperature in the intranasal drainage group was shorter than that in the traditional group [(6.1±1.5) d vs. (9.1±1.9) d], and the difference was statistically significant ( t = 5.02, P < 0.001). The usage time of antibiotic in the intranasal drainage group was shorter than that in the traditional group [(11.5±1.9) d vs. (14.2±2.7) d], and the difference was statistically significant ( t = 3.30, P < 0.001). Anastomotic fistula healing time in the intranasal drainage group was shorter than that in the traditional group [(20±4) d vs. (24±6) d], and the difference was statistically significant ( t = 2.32, P < 0.05). The hospitalization stay in the intranasal drainage group was shorter than that in the traditional group [(27±3) d vs. (36±7) d],and the difference was statistically significant ( t = 5.20, P < 0.001). There was no statistically significant difference in the incidence of anastomotic stenosis between the 2 groups after treatment ( P > 0.05). Conclusions:Intranasal drainage is a simple and effective treatment method for patients with anastomotic fistula and abscesses that are not easily drained in thoracic cavity or mediastinum after resection surgery of esophageal cancer.
