Progress of circulating tumor cells in breast cancer
10.3760/cma.j.cn115355-20231129-00211
- VernacularTitle:循环肿瘤细胞在乳腺癌中的研究进展
- Author:
Yongmei ZHANG
1
;
Gang GUO
;
Huayi ZHANG
Author Information
1. 内蒙古医科大学附属医院检验科,呼和浩特 010050
- Keywords:
Breast neoplasms;
Circulating tumor cells;
Neoplasm metastasis
- From:
Cancer Research and Clinic
2024;36(10):797-800
- CountryChina
- Language:Chinese
-
Abstract:
Circuating tumor cells (CTC) are cells that are shed from the primary sites of malignancies and enter the bloodstream through the blood vessel or lymphatic system. The formation of CTC is a key step in the tumor metastasis process. CTC can reflect the heterogeneity of solid tumors in time and space, and can be used as an important supplementary method for pathological diagnosis, prognostic interpretation, disease detection and molecular typing. Some researchers also apply CTC to carry out culture in vitro, functional detection and histochemical analysis. This article reviews the recent research of CTC in diagnosis and assessment of efficacy, prognosis and metastasis of breast cancer.