Clinicopathological and imaging features of 9 cases with ovarian collision tumors
10.3760/cma.j.cn115355-20231120-00196
- VernacularTitle:卵巢碰撞瘤9例临床病理及影像学特征分析
- Author:
Xi ZHANG
1
;
Xiaojuan WANG
;
Chunyan WANG
;
Pei WANG
Author Information
1. 山西省肿瘤医院 中国医学科学院肿瘤医院山西医院 山西医科大学附属肿瘤医院核医学科，太原 030013
- Keywords:
Ovarian neoplasms;
Ovarian collision tumors;
Pathology, clinical;
Diagnostic imaging
- From:
Cancer Research and Clinic
2024;36(8):594-599
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinicopathological characteristics and imaging manifestations of ovarian collision tumors.Methods:A retrospective case series study was conducted. The clinical data of 9 patients with ovarian collision tumors diagnosed by surgical pathology and with complete clinical and imaging data from Shanxi Province Cancer Hospital betweenJanuary 2013 and December 2021 were retrospectively analyzed. Tumor markers, ultrasound and CT examinations were performed in all patients. Ovarian-adnexal reporting and data system (O-RADS) scoring was used to observe the imaging features of tumors, and to make comparison with clinical features and pathological results.Results:The median age [ M ( Q1, Q3)] of the 9 patients was 42 years (29 years, 64 years); clinical symptoms included lower abdominal pain, suffocation with lumbar drowsiness in 2 cases, vaginal bleeding in 1 case, intermittent malaise and vomiting in 1 case, and asymptomatic in 5 cases; 2 cases had elevated carbohydrate antigen 125 (CA125), 1 case had elevated carbohydrate antigen 199 (CA199), 1 case had elevated carcinoembryonic antigen (CEA), CA199 and CA125, and 1 case had elevated CEA, CA199, and human epitope protein 4 (HE4). O-RADS scoring: 4 cases had 2 points, 2 cases had 3 points, 3 cases had 4 points. CT result showed a large or huge cystic solid lesion, with tumor diameter of 3-25 cm, a smooth edge and a variety of density or signal components in 9 cases. All the 9 cases were composed of germ cell-derived and surface epithelial-derived tumors. Conclusions:The clinical symptoms and imaging manifestations of ovarian collision tumors are non-specific. O-RADS scoring plays a certain role in predicting the nature of ovarian collision tumors. Its pathological types are mostly germ cell-derived tumors and surface epithelial-derived tumors.
