Research progress of biological markers for immunotherapy in patients with pancreatic cancer
10.3781/j.issn.1000-7431.2024.2305-0245
- VernacularTitle:胰腺癌免疫治疗生物标志物的研究进展
- Author:
Anyi JIANG
1
;
Yuzhi LIU
;
Ming QUAN
Author Information
1. 同济大学附属东方医院肿瘤科,上海 200120
- Keywords:
Pancreatic cancer;
Immunotherapy;
Biomarker
- From:
Tumor
2024;44(1):77-88
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is one of the common gastrointestinal malignancies,the incidence of which is increasing year by year and has become one of the most important public health problems worldwide.At present,tumor treatment has entered the era of immunotherapy,but the response of pancreatic cancer patients to immune checkpoint inhibitors is not ideal.In addition,there is a lack of effective and validated biomarkers to stratify patients who may benefit from immunotherapy.This review has summarized the current research advances of immunotherapeutic biomarkers in pancreatic cancer,hoping to help clinicians understand relevant biomarkers systematically and guide the precise treatment of pancreatic cancer.