Recognition and Practice of Traditional Chinese Medicine in Intestinal Graft-Versus-Host Disease
10.16466/j.issn1005-5509.2024.09.007
- VernacularTitle:肠道移植物抗宿主病中医辨识与实践
- Author:
Yiwen FANG
1
;
Shisi SHAO
;
Baodong YE
Author Information
1. 浙江中医药大学第一临床医学院 杭州 310053
- Keywords:
graft-versus-host disease;
allogeneic hematopoietic stem cell transplantation;
enteropathy;
strengthening the body resistance and resolving pathogen;
experience of famous doctors;
Chinese medicine therapy;
QIN Danping
- From:
Journal of Zhejiang Chinese Medical University
2024;48(9):1110-1115
- CountryChina
- Language:Chinese
-
Abstract:
[Objective]To summarize Professor QIN Danping's experience in applying traditional Chinese medicine to treat intestinal graft-versus-host disease.[Methods]Through following Professor QIN's outpatient service,collecting and sorting out medical cases,the academic characteristics of Professor QIN in treatment of intestinal graft-versus-host disease were summarized from the aspects of disease cognition,syndrome evolution and clinical treatment,and the medical cases were attached to support it.[Results]It is believed that the patient of transplant is the subject,the transplanted allogeneic hematopoietic stem cells are the objects and spleen deficiency is the basis.After transplantation,the object enter the body to produce dampness,heat,cold,stasis and toxin,which act on the intestine to cause disease.The pathogenesis of the disease is root deficiency and branch excess.Treatment emphasizes both symptoms and root causes,invigorating the spleen and supplementing Qi is basic treatment principle,dispelling dampness,regulating cold and heat,regulating Qi and dissolving stasis are manifestations,to make the vital Qi and evil Qi mutually inclusive and the disease achieve stable.The medical cases mentioned were acute gastrointestinal graft-versus-host disease and chronic intestinal graft-versus-host disease,were treated by strengthening the spleen and clearing dampness-heat,harmonizing stomach and stopping diarrhea,regulating cold and heat,strengthening the spleen to control diarrhea separately,and both cases achieved significant effect.[Conclusion]Professor QIN aims at making the ontology and foreign body mutually inclusive,adopts"strengthening the body resistance and resolving pathogen"as the core in the treatment of intestinal graft-versus-host disease,improves clinical symptoms and alleviates the intestinal mucosal inflammation,which is worth further exploration.
