Efficacy of cosmetic suturing techniques combined with topical recombinant human basic fibroblast growth factor in repairing facial trauma
10.3760/cma.j.issn.1671-0290.2024.06.011
- VernacularTitle:美容缝合技术联合外用重组人碱性成纤维细胞生长因子修复面部外伤的疗效观察
- Author:
Huibin LIAN
1
;
Pingsong LI
;
Kunjie RONG
;
Gang XU
;
Jie ZHOU
;
Yi LUO
;
Zhongyin ZHUFU
;
Haibin JU
;
Junjun JIN
;
Rui JIAO
;
Xiaowei ZHANG
;
Zhimin YIN
Author Information
1. 苏北人民医院烧伤整形科,扬州 225001
- Keywords:
External injury;
Cosmetic suture technique;
Recombinant human basic fibroblast growth factor for external use;
Heart-shaped suture;
Scar
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2024;30(6):571-575
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of cosmetic suturing techniques combined with topical recombinant human basic fibroblast growth factor (rh-bFGF) in repairing facial trauma.Methods:A prospective study was conducted on 140 patients with facial trauma admitted to the Department of Burn and Plastic Surgery, Northern Jiangsu People's Hospital from January to December 2022. Patients were divided into two groups based on different treatment methods using a random number table method: treatment group (70 cases), including 38 males and 32 females aged 3 to 54 (23.1±8.2) years, received cosmetic suturing techniques combined with topical rh-bFGF for wound repair; control group (70 cases), including 36 males and 34 females aged 2 to 49 (22.3±7.5) years, only received cosmetic suturing techniques for wound repair. Patients were followed up 2 weeks post-surgery to evaluate wound healing quality. Patient satisfaction was assessed using the visual analogue scale (VAS). Six months post-surgery, scar conditions were evaluated using the Vancouver scar scale (VSS).Results:In the treatment group, 65 cases were directly sutured, and 5 cases were repaired with skin flaps, with a first-class healing rate of 100% (70/70). In the control group, 66 cases were directly sutured, and 4 cases were repaired with skin flaps, with a first-class healing rate of 91.4% (64/70). The first-class healing rate in the treatment group was higher than that in the control group, with a statistically significant difference ( P=0.037). Two weeks post-surgery, the VAS score for surgical satisfaction in the treatment group was (1.13±0.52) scores, which was lower than that in the control group (2.56±1.32) scores, with a statistically significant difference ( P<0.001). Six months post-surgery, the VSS score for the treatment group was (2.49±1.27) scores, which was lower than that in the control group (4.67±1.93) scores, with a statistically significant difference ( P<0.001). Conclusions:In repairing facial trauma, the combination of cosmetic suturing techniques and topical rh-bFGF can improve wound healing quality, reduce wound scarring, and enhance patient satisfaction with surgery.