Screening process of breast implant associated-anaplastic large cell lymphoma in symptomatic patients with textured breast implants
10.3760/cma.j.issn.1671-0290.2024.04.012
- VernacularTitle:有症状毛面乳房植入物相关的间变性大细胞淋巴瘤的筛查流程研究
- Author:
Wenchao ZHANG
1
;
Jiangmiao XIE
;
Zenan XIA
;
Mingzi ZHANG
;
Xiao LONG
;
Xiaojun WANG
;
Ang ZENG
Author Information
1. 中国医学科学院 北京协和医院整形外科，北京 100730
- Keywords:
Prosthesis implantation;
Textured breast implant;
Screening;
Anaplastic large cell lymphoma;
T-cell non-Hodgkin Lymphoma
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2024;30(4):354-358
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the clinical diagnosis and treatment process of breast implant associated-anaplastic large cell lymphoma (BIA-ALCL) in symptomatic patients with textured breast implants in Peking Union Medical College Hospital in order to provide reference for the management of such patients in China.Methods:From January 2019 to September 2021, 23 symptomatic patients with textured breast implants were admitted to the Peking Union Medical College Hospital, aged 29-52 years, with an average of 36.2 years. All patients agreed to remove the prosthesis by surgery, and accepted cytology, flow cytometry, and immunohistochemical examination of the fluid around the implants and capsule tissue before or during the operation to complete the BIA-ALCL screening process.Results:All 23 patients presented with unilateral periprosthetic fluid accumulation, with fluid volume ranging from 20 to 130 ml, of which 7 cases were combined with periprosthetic contracture. No tumor cells were found in the pathological findings of effusion and the capsule tissue, and the BIA-ALCL pathologic screening results (CD 30 and ALK) were all negative. No bleeding, infection, wound dehiscence and other complications occurred after the operation.Conclusions:A personalized clinical process should be developed for symptomatic patients with textured breast implants. Attention should be paid to imaging and pathological examinations.
