Therapeutic effect of CO 2 fractional laser with topical triamcinolone and intrakeloid injection of triamcinolone on keloid
10.3760/cma.j.issn.1671-0290.2024.03.019
- VernacularTitle:CO 2点阵激光与曲安奈德联合治疗瘢痕疙瘩的效果观察
- Author:
Xiaoxue HAN
1
;
Pan ZHANG
;
Fei ZHENG
Author Information
1. 北京美天医疗美容医院，北京 100030
- Keywords:
Keloid;
CO 2 fractional laser;
Triamcinolone;
Intradermal injection;
Treatment outcome
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2024;30(3):278-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the therapeutic effect of CO 2 fractional laser with topical triamcinolone and intrakeloid injection of triamcinolone. Methods:From January 2019 to December 2021, 24 cases of keloid patients in the outpatient clinic of the Department of Plastic Surgery and Aesthetics Hospital, all female, aged 22-53 years, were randomly divided into treatment group 1 (12 cases), treated with CO 2 fractional laser + local topical triamcinolone, and treatment group 2 (12 cases), treated with intra-local triamcinolone injection. The treatment was done every 4 weeks for 4-9 times and followed up for 1 year. Keloid size was assessed before and after each treatment and scarring was evaluated with the Vancouver Keloid Scale. Results:After treatment, the change in keloid size was greater in the treatment group 2 than that in the treatment group 1 (85.4% and 60.1%, χ 2=6.19, P<0.05), and the Vancouver Keloid Scale score showed that it was significantly lower in the treatment group 1 (7.8±1.5 versus 4.4±1.3, t=4.58, P<0.05) compared with the treatment group 2 (8.6±0.9 versus 4.5±1.3, t=3.45, P<0.05). During and at the end of treatment, the pain scores of the treatment group 1 were significantly lower than those of the treatment group 2, and patients′ comfort and compliance were significantly improved. Conclusions:Fractional laser combined with topical triamcinolone is a more suitable treatment option for patients with pain-sensitive keloids.
