Progress on the diagnosis and treatment of Exosomes in Idiopathic Pulmonary Fibrosis
10.3760/cma.j.cn114452-20240130-00061
- VernacularTitle:外泌体在特发性肺纤维化中的诊疗研究进展
- Author:
Yuan QI
1
;
Chao WANG
;
Xiuru GUAN
Author Information
1. 哈尔滨医科大学第一附属医院检验诊断科，哈尔滨 150001
- Keywords:
Pulmonary fibrosis;
Idiopathic pulmonary fibrosis;
Exosomes;
Different cells;
Body fluid;
Diagnosis;
Prognosis
- From:
Chinese Journal of Laboratory Medicine
2024;47(10):1225-1230
- CountryChina
- Language:Chinese
-
Abstract:
Idiopathic Pulmonary Fibrosis is a chronic interstitial lung disease of unknown etiology with a short survival period, poor prognosis, and difficult to completely cure. At present, the main diagnostic method of IPF is High Resolution CT (HRCT), which has the disadvantage of high subjective impact and low repeatability. Therefore, it is necessary to develop novel biomarkers to aid in the diagnosis and prognosis of IPF. In recent years, more and more studies have focused on exosomes, whose specific regulatory mechanisms for IPF have not been fully elucidated, although it has been extensively studied in the field of malignant tamors and cardiovascular disease. In addition, exosomes can be secreted by different cells and body fluids, having potential applications in suggesting IPF risk and diagnostic prognosis.
