A case of green urine in the qualitative analysis of urinary protein caused by elevated urinary copper in a patient with choledochal adenocarcinoma

VernacularTitle:胆总管腺癌患者尿铜升高引起尿蛋白定性过程中尿色变绿1例
Author: Yi CHENG ¹ ; Shiying LIU ; Liping ZHOU ; Ming LIU ; Wurong HUANG ; Fuqiang SONG
Author Information

1. 西部战区总医院检验科，成都　610083
Keywords: Adenocarcinoma; Obstructive jaundice; Urinary copper; Sulfosalicylic acid
From: Chinese Journal of Laboratory Medicine 2024;47(8):966-968
CountryChina
Language:Chinese
Abstract: A middle-aged female with abnormal liver function indicators was admitted to hospital with obstructive jaundice. Urine protein of the patient was positive, and the color turned green during the retest with sulfosalicylic acid, which was relatively rare. According to the laboratory examination and other auxiliary diagnosis of the patient, the cause of the discoloration was found to be obstructive jaundice induced by choledochal adenocarcinoma, which impeded the excretion of copper ions through the bile of the patient. Copper enters the urine through the circulation of the bile, causing an increase in urinary copper. This provides a theoretical basis for the discovery of this phenomenon in clinical tests.