Current research situation, challenges and development trends of extracellular vesicles in the field of laboratory medicine
10.3760/cma.j.cn114452-20240705-00355
- VernacularTitle:细胞外囊泡在检验医学领域的研究现状、挑战与发展趋势
- Author:
Bo LI
1
;
Yiyao HUANG
;
Qi XIU
;
Lei ZHENG
Author Information
1. 南方医科大学南方医院检验医学科，广州510515
- Keywords:
Extracellular vesicles;
Laboratory medicine;
Current applications;
Development trends
- From:
Chinese Journal of Laboratory Medicine
2024;47(8):837-843
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles (EV), as novel disease biomarkers, have shown broad applicational prospect in the field of laboratory medicine or disease diagnosis. There have been substantial advancements in EV isolation technologies, EV biomarker screening and validation, and EV detection techniques. However, to fully integrate EV into clinical laboratories, ongoing efforts are needed in several areas including multi-omics integration and big data analysis, the development of clinically suitable technologies in isolation and detection, the establishment of standardized and normalization of quality systems, and the execution of clinical trials and administration and approvals of products, so as to promote the application and transformation of EV detection technologies in disease diagnosis, therapeutic evaluation, and prognosis assessment, thereby fostering better service of people's health in the aspect of laboratory medicine.
