Influencing factors and current status of diagnosis and treatment of Ureaplasma infection
10.3760/cma.j.cn114452-20230907-00123
- VernacularTitle:脲支原体属感染的影响因素与诊治现状
- Author:
Rongdan CHEN
1
;
Yingxuan ZHANG
;
Wei QING
;
Wenyu MO
;
Hongwei ZHOU
;
Muxuan CHEN
Author Information
1. 南方医科大学珠江医院检验医学部，微生态医学中心，广州510280
- Keywords:
Ureaplasma;
Ureaplasma urealyticum;
Ureaplasma parvum;
Biovar;
Serovar;
Pathogenicity;
Resistance
- From:
Chinese Journal of Laboratory Medicine
2024;47(6):706-712
- CountryChina
- Language:Chinese
-
Abstract:
Ureaplasma is a common pathogen in the human reproductive tract and consists of two distinct biotypes: biotype 1 and biotype 2. In 2002, based on the differences between biotypes, biotype 1 was further classified to a separate species named Ureaplasma parvum (Up), whereas biotype 2 is referred to as Ureaplasma urealyticum (Uu). Uu infection is associated with various urogenital diseases including infertility, preterm birth, and urethritis, while the pathogenicity of Up remains controversial. Researches have shown that different serotypes showed distinct pathogenicity and drug resistance in different diseases and populations, highlighting the importance of clinical tests of serotype and biotype for Ureaplasma. This article reviews the factors that may be associated with Ureaplasma infection, and the current status of the diagnosis and treatment in clinical practice, aiming to provide insights into the clinical significance and necessity of biotypes and serotype tests for Ureaplasma-positive cases and to serve as a reference for the clinical diagnosis and treatment of related diseases.
