Research progress of clinical symptoms and treatment of primary uveal mucosa-associated lymphoid tissue lymphoma
10.3760/cma.j.cn511434-20240305-00091
- VernacularTitle:原发性葡萄膜黏膜相关淋巴组织淋巴瘤的临床表现及治疗的研究进展
- Author:
Xin CHEN
1
;
Lili ZHANG
;
Ting ZHANG
;
Qian CHEN
;
Yingwen BI
;
Gezhi XU
Author Information
1. 复旦大学附属眼耳鼻喉医院眼科 国家卫生健康委员会近视眼重点实验室 上海市视觉损害与重建重点实验室, 上海 200031
- Keywords:
Mucosa-associated lymphoid tissue lymphoma;
B-cell;
Marginal zone;
Uveal neoplasms;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2024;40(8):656-662
- CountryChina
- Language:Chinese
-
Abstract:
Mucosa-associated lymphoid tissue (MALT) lymphoma is an indolent B cell derived non-Hodgkin's lymphoma. It is the main type of uveal lymphoma and is extremely rare. The pathogenesis of ocular MALT lymphoma remains unclear. It is now considered to be associated with many causes. The manifestations of primary uveal MALT lymphoma differ. So sometimes it is necessary to diagnose depending on diversity of auxiliary tests. Ultrasound examination shows typical low and homogeneous internal reflectivity, with blood flow signal. Optical coherence tomography, fundus imaging, fundus angiography, magnetic resonance imaging and positron emission tomography computerized tomography can assist diagnosing. Primary uveal MALT lymphoma is sensitive to radiation therapy, chemotherapy and biotherapy have positive influence too. The prognosis of uveal MALT lymphoma is good, but its early diagnosis is rather challenging. The nonspecific clinical manifestations and the rarity of the disease can confound the initial diagnosis, resulting in delayed treatments which may cause irreversible vision loss.
