Research progress and clinical application of adaptive optics in retinal imaging
10.3760/cma.j.cn511434-20240407-00141
- VernacularTitle:自适应光学技术的研究进展及其在眼底影像学中的临床应用
- Author:
Qi FANG
1
;
Lei ZHANG
;
Haiyan WANG
;
Ru WANG
Author Information
1. 西安医学院, 西安 710021
- Keywords:
Adaptive optics;
Imaging;
Retinal disease;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2024;40(8):645-650
- CountryChina
- Language:Chinese
-
Abstract:
As a newly developing technology of adaptive optics (AO), the combination of AO technology with traditional fundus imaging devices, such as fundus camera, scanning laser ophthalmoscope as well as optical coherence tomography, can image photoreceptor cells, retinal pigment epithelial cells, retinal ganglion cells, and retinal vascular system. Currently, AO technology is applied in the diagnosis, monitor and management of retinal diseases, enabling the observation of early changes of photoreceptor cells and analyzing vascular parameters in inherited retinal diseases, age-related macular degeneration, retinal vascular diseases such as diabetic retinopathy and retinal vein occlusion, inflammatory retinal diseases and central serous chorioretinopathy. Major breakthrough brought by AO technology along with rapid progress driven by ophthalmic imaging devices can help clarify the pathogenesis of eye diseases. and offer a comprehensive understanding of the new perspectives provided by AO technology for fundus imaging. Of course, limitation of popularizing application of AO device exists due to small scan range and optic media opacity. Thus, a comprehensive understanding of AO technology provides a new horizon for retina imaging. A comprehensive understanding of AO technology provides updated vision for fundus imaging, and is expected to promote the clinical application of AO technology in ophthalmology, and to enable cellular-resolution imaging of the living human retina.
