Surgical treatment of isolated pulmonary mucormycosis
10.3760/cma.j.cn112434-20240618-00162
- VernacularTitle:局限性肺毛霉菌病的外科治疗
- Author:
Weipeng ZHU
1
;
Fan YANG
;
Jiashun CAO
;
Xianming HOU
;
Ting ZHOU
;
Zimu ZHANG
;
Donghong CHEN
Author Information
1. 清华大学附属北京清华长庚医院 清华大学临床医学院胸外科，北京 102218
- Keywords:
Mucormycosis;
Lung resection;
Surgical treatment
- From:
Chinese Journal of Thoracic and Cardiovascular Surgery
2024;40(10):612-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To retrospectively analyze the surgical treatment of isolated pulmonary mucormycosis, explore the timing and effect of operation.Methods:Clinical data of patients with isolated pulmonary mucormycosis who underwent surgical treatment from April 2019 to April 2024 were collected and retrospectively analyzed, combined with literature review.Results:The clinical data of 13 patients with pulmonary mucormycosis who underwent operation were collected, including 9 males and 4 females, aged 22~64(45.4±15.4)years old. The basic diseases included diabetes mellitus in 10 cases and hematological malignancy in 3 cases. Seven patients had hemoptysis during the course of the disease. All 13 patients received adequate antifungal therapy before surgery, and 12 patients received bronchoscopic interventional therapy. Ten patients underwent lobectomy, two underwent pneumonectomy, and one underwent a right sleeve pneumonectomy. All patients were cured except one patient with bronchopleural fistula after operation. All patients achieved complete elimination of mucor and also discontinuation of antifungal drug.Conclusion:For isolated pulmonary mucormycosis, on the basis of systemic antifungal treatment, actively seek the opportunity of surgical intervention, can shorten the course of the disease and achieve good therapeutic results.
