Pathogen spectrum of hospitalized severe acute respiratory infection cases in a sentinel hospital in Tongzhou District of Beijing from 2019 to 2022
10.3760/cma.j.cn112309-20240310-00079
- VernacularTitle:2019—2022年北京市通州区严重急性呼吸道感染住院病例病原谱分析
- Author:
Lin ZOU
1
;
Chong ZHANG
;
Ling TONG
;
Jianming ZHANG
;
Jianguo WANG
;
Fang WANG
;
Xiang GAO
;
Shujuan CUI
;
Daitao ZHANG
Author Information
1. 北京市通州区疾病预防控制中心微生物检验科，北京 101100
- Keywords:
Severe acute respiratory tract infection;
Influenza A virus;
Respiratory syncytial virus;
Mycoplasma pneumoniae;
Stenotrophomonas maltophilia
- From:
Chinese Journal of Microbiology and Immunology
2024;44(7):596-600
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the pathogen spectrum and the epidemiological characteristics of hospitalized severe acute respiratory tract infection (SARI) cases in a sentinel hospital in Tongzhou District of Beijing from 2019 to 2022, and provide reference for scientific prevention and control of SARI.Methods:This study enrolled SARI patients in the Beijing Luhe Hospital from January 2019 to December 2022. Nasopharyngeal swabs or respiratory secretions of the patients were collected and analyzed by quantitative real-time PCR to detect the pathogens and their types. The epidemiological and clinical characteristics of the cases were analyzed.Results:In this study, 1 124 SARI cases were enrolled, of which 379 were positive for respiratory pathogens with a detection rate of 33.72%. Most of the SARI cases were positive for bacteria pathogens, and the detection rates of Mycoplasma pneumoniae, Streptococcus pneumoniae, and Stenotrophomonas maltophilia were high. Influenza A virus, parainfluenza virus, and respiratory syncytial virus were the main viral pathogens detected in the cases. There were significant differences in the number of cases and the detection rate of respiratory pathogens among different age groups (χ 2=555, P=0.000 1). The predominant pathogens in different years were different. Mycoplasma pneumoniae [27.27% (51/187)] and influenza A virus [17.65% (33/187), ] were the predominant pathogens in 2019; parainfluenza virus [16.67% (10/60)], Mycoplasma pneumoniae [11.67% (7/60)], and Haemophilus influenzae [11.67% (7/60)] were the predominant pathogens in 2020; Stenotrophomonas maltophilia [24.39% (20/82)] and respiratory syncytial virus [19.51% (16/82)] were the predominant pathogens in 2021; Stenotrophomonas maltophilia [20% (10/50)] and parainfluenza virus [12% (6/50)] were the predominant pathogens in 2022. Conclusions:Most of the SARI cases in Tongzhou district of Beijing from 2019 to 2022 are caused by bacteria. More attention should be paid to the prevalence of Stenotrophomonas maltophilia and Mycoplasma pneumoniae, as well as the prevalence of respiratory syncytial virus, parainfluenza virus, and influenza A virus. The predominant pathogens change every year from 2019 to 2022. Therefore, the prevention and control strategies should be made accordingly. This study provides basis data for the national respiratory multipathogen surveillance program.
