Prospectives of nucleic acid vaccine technology platform in preventive vaccine development
10.3760/cma.j.cn112309-20240419-00139
- VernacularTitle:核酸疫苗技术平台在预防性疫苗开发中的前瞻性观点
- Author:
Xuanyi WANG
1
;
Bin WANG
;
Sidong XIONG
;
Xiaoming GAO
;
Yucai PENG
;
Xia JIN
;
Tao ZHU
;
Bo YING
;
Wei CUN
;
Chunlai JIANG
;
Jiyun YU
;
Ze CHEN
;
Jianjun CHEN
;
Chunlin XIN
Author Information
1. 复旦大学生物医学研究院,上海市重大传染病和生物安全研究院,上海 200032
- Keywords:
Nucleic Acid;
Immune protection mechanism;
Safety;
Preventability;
Vaccine
- From:
Chinese Journal of Microbiology and Immunology
2024;44(7):565-572
- CountryChina
- Language:Chinese
-
Abstract:
In November 2023, the seventh National Nucleic Acid Vaccine Conference was held to deeply discuss the immune mechanism, safety risks, advantages, and disadvantages of nucleic acid vaccines, and review the safety and effectiveness of COVID-19 vaccines developed by nucleic acid vaccine technology. Some prospectives were formed in the meeting that in the post-pandemic era, nucleic acid vaccine technology will play a role in the following areas: dealing with pathogens that are difficult to be prevented by traditional vaccines, promoting the upgrading of traditional live attenuated vaccines, contributing to the development of multivalent and combined vaccines, and rapid response to emerging and re-emerging infectious diseases. These views point out the direction for the future development of nucleic acid vaccine technology.