The effects of exercise on inflammation, endothelium function and the blood pressure of middle-aged persons with hypertension
10.3760/cma.j.cn421666-20240624-00161
- VernacularTitle:不同运动方式对中年高血压患者炎症反应、内皮功能及动态血压的影响
- Author:
Zhijun YANG
1
;
Shanchang REN
;
Jinhua YANG
;
Xiaoyang NIU
Author Information
1. 商丘师范学院体育学院，商丘 476000
- Keywords:
Aerobic exercise;
Resistance training;
Hypertension;
Inflammation;
Endothelial functioning;
Blood pressure
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2024;46(11):967-972
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the effects of different exercise modes on inflammation, endothelium functioning and the ambulatory blood pressure (ABP) of middle-aged hypertensive patients, so as to provide a basis for optimizing rehabilitation training prescriptions.Methods:Ninety persons with hypertension were randomly divided into an aerobic exercise group, a resistance training group and a control group, each of 30. All maintained their routine daily living habits and medications. In addition, the aerobic exercise group performed aerobic exercise, while the resistance training group took resistance exercise for twelve weeks. Inflammatory response, endothelium functioning and 24-hour ABP were evaluated before and after the experiment.Results:The subjects tolerated the different exercises well. After the experiment, the daytime systolic blood pressure (SBP) and 24-hour SBP of those in both exercise groups had decreased significantly, on average. Flow-mediated dilation had increased significantly. The average plasma nitric oxide and interleukin-10 levels had increased significantly, and the average C-reactive protein, monocyte chemoattractant protein-1, vascular cell adhesion molecule-1, lectin-like oxidized LDL receptor-1, and endothelin-1 levels had decreased significantly in the aerobic exercise group, but not in the control group.Conclusions:Both regular aerobic exercise and resistance training benefit blood pressure control and reduce the risk of cardiovascular disease, at least among middle-aged persons with hypertension. Aerobic exercise tends to have the better effect.
