Intermittent theta burst stimulation of the bilateral cerebellum can relieve post-stroke dysphagia
10.3760/cma.j.issn.0254-1424.2024.08.006
- VernacularTitle:双侧小脑间歇性θ爆发刺激治疗脑梗死后吞咽障碍的临床研究
- Author:
Yuejiao CAO
1
;
Weiguan CHEN
;
Zhidong HUANG
;
Qian XU
;
Fang CAO
;
Dongyan ZHU
;
Huiyuan JI
;
Dehui XU
;
Hongjian LU
Author Information
1. 南通市第一人民医院康复医学科，南通 226000
- Keywords:
Theta-burst stimulation;
Cerebellum;
Cerebral infarction;
Dysphagia
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2024;46(8):706-711
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of intermittent theta burst stimulation (iTBS) of the bilateral cerebellum in treating post-stroke dysphagia.Methods:Forty patients with dysphagia after a cerebral infarction were randomly divided into a control group and an iTBS group, with 20 cases in each group. In addition to routine swallowing rehabilitation training and nutritional guidance, the iTBS group underwent daily bilateral cerebellar iTBS 6 times a week for 3 weeks, while the control group was given sham stimulation. Before and after the treatment, both groups were evaluated by using the water-swallowing test and the standardized swallowing assessment (SSA), and the latency and amplitude of the mylohyoid muscle′s motor evoked potential (MEP) were also recorded. The SSA scores and MEP amplitudes of the mylohyoid muscle after treatment were tested for any correlation.Results:The treatment improved the water-swallowing test results in both groups, with that of the iTBS group significantly better than that of the control group. The clinical efficacy in the iTBS group was 95%, significantly higher than the control group′s 80%. The SSA scores decreased significantly in both groups after the treatment, with the iTBS group′s average score then significantly lower than that of the control group. The average latency and amplitude of the mylohyoid muscle′s MEP was also significantly better in the iTBS group after the treatment. In the control group only the average amplitude was significantly greater than before the treatment. Pearson correlation analysis showed that the SSA scores and the MEP amplitudes of the mylohyoid muscle after treatment were uncorrelated in both groups.Conclusions:Bilateral intermittent theta burst stimulation can effectively improve the swallowing of patients with post-stroke dysphagia.
