Intermittent feeding through an oral to esophageal tube is best for patients with a late-onset swallowing disorder after radiotherapy
10.3760/cma.j.issn.0254-1424.2024.06.009
- VernacularTitle:间歇经口至食管管饲对鼻咽癌放疗后迟发性吞咽障碍的影响
- Author:
Hongji ZENG
1
;
Xi ZENG
;
Weijia ZHAO
;
Jihong WEI
;
Furong BAO
;
Heping LI
;
Liugen WANG
Author Information
1. 郑州大学公共卫生学院，郑州 450000
- Keywords:
Nasopharyngeal carcinoma;
Swallowing disorders;
Tube feeding;
Radiotherapy
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2024;46(6):534-538
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the clinical efficacy of intermittent feeding through an oral to esophageal (IOE) tube for persons with a late-onset swallowing disorder after radiotherapy for nasopharyngeal carcinoma.Methods:Fifty-six patients with late-onset swallowing difficulties after radiotherapy for nasopharyngeal carcinoma were divided at random into an observation group and a control group, each of 28. In addition to conventional therapy, the controls were fed through an indwelling nasogastric tube (NGT) while an IOE tube was used in the observation group. The nutritional status of the two groups was compared after 20 hours and after 15 days of treatment. Depression, oral feeding ability, leakage and aspiration, and life quality were evaluated using patient health questionnaire-9 (PHQ-9), a functional oral feeding scale (FOIS), a leakage-aspiration scale (PAS), and a swallowing-quality of life (SWAL-QOL) evaluation. From the 3rd day after admission the daily amount fed was recorded.Results:At admission there were no significant differences between the two groups. After 15 days, however, there was significantly greater improvement observed in the average serum albumin, hemoglobin, serum total protein, serum prealbumin level, body mass index(BMI) and SWAL-QOL score of the experimental group compared to the control group, with significantly fewer members suffering from depression. From the 4th day after admission the observation group′s members ate a significantly larger proportion of the target feeding amount.Conclusion:IOE feeding can improve the nutritional status, psychological status, and life quality of persons with a late-onset swallowing disorder more effectively than NGT feeding, with a lower incidence of adverse events.
