Background, design, and preliminary implementation of China prospective multicenter birth cohort
- VernacularTitle:中国前瞻性多中心出生队列的建设背景、设计和初步实施
- Author:
Si ZHOU
1
;
Liping GUAN
;
Hanbo ZHANG
;
Wenzhi YANG
;
Qiaoling GENG
;
Niya ZHOU
;
Wenrui ZHAO
;
Jia LI
;
Zhiguang ZHAO
;
Xi PU
;
Dan ZHENG
;
Hua JIN
;
Fei HOU
;
Jie GAO
;
Wendi WANG
;
Xiaohua WANG
;
Aiju LIU
;
Luming SUN
;
Jing YI
;
Zhang MAO
;
Zhixu QIU
;
Shuzhen WU
;
Dongqun HUANG
;
Xiaohang CHEN
;
Fengxiang WEI
;
Lianshuai ZHENG
;
Xiao YANG
;
Jianguo ZHANG
;
Zhongjun LI
;
Qingsong LIU
;
Leilei WANG
;
Lijian ZHAO
;
Hongbo QI
Author Information
- Keywords: Cohort studies; Birth cohort; Prospective study; Multi-center study; Multi-omics study
- From: Chinese Journal of Perinatal Medicine 2024;27(9):750-755
- CountryChina
- Language:Chinese
- Abstract: China prospective multicenter birth cohort (Prospective Omics Health Atlas birth cohort, POHA birth cohort) study was officially launched in 2022. This study, in collaboration with 12 participating units, aims to establish a high-quality, multidimensional cohort comprising 20 000 naturally conceived families and assisted reproductive families. The study involves long-term follow-up of parents and offspring, with corresponding biological samples collected at key time points. Through multi-omics testing and analysis, the study aims to conduct multi-omics big data research across the entire maternal and infant life cycle. The goal is to identify new biomarkers for maternal and infant diseases and provide scientific evidence for risk prediction related to maternal diseases and neonatal health.
