Morning Hypertension in Treated Hypertensives: Baseline Characteristics and Clinical Implications.
10.4070/kcj.2011.41.12.733
- Author:
Ju Hee LEE
1
;
Jang Whan BAE
;
Jung Bae PARK
;
Chang Gyu PARK
;
Ho Joong YOUN
;
Dong Ju CHOI
;
Young Keun AHN
;
Joon Han SHIN
;
Se Joong RIM
;
Jang Ho BAE
;
Dong Woon KIM
Author Information
1. Cardiovascular Center of Chungbuk National University Hospital, Cheongju, Korea. kdwoon@chungbuk.ac.kr
- Publication Type:Original Article
- Keywords:
Home Blood Pressure Monitoring
- MeSH:
Antihypertensive Agents;
Blood Pressure;
Blood Pressure Monitoring, Ambulatory;
Body Mass Index;
Fasting;
Glucose;
Humans;
Hypertension;
Male;
Waist Circumference;
Waist-Hip Ratio
- From:Korean Circulation Journal
2011;41(12):733-743
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: Morning hypertension is closely related to target organ damage and cardiovascular events. Little data is available concerning the baseline characteristics and comprehensive blood pressure analysis of hypertensive patients on treatment with morning hypertension. SUBJECTS AND METHODS: We evaluated 1,087 hypertensive patients who had taken stable anti-hypertensive medication at least 6 months. The enrolled patients measured their home blood pressure for 7 days. Baseline characteristics and the laboratory data were analyzed. Morning hypertension was defined as a morning blood pressure > or =135/85 mm Hg and systolic or diastolic blood pressure difference between morning and evening exceeding 10 mm Hg. RESULTS: One hundred seventy three patients with morning hypertension showed a preponderance of males, older patients, alcohol consumers, and greater waist circumference and waist-to-hip ratio despite the same body mass index. Impaired fasting glucose and metabolic syndrome were more prevalent in the patients with morning hypertension. The morning hypertensives took more anti-hypertensive drugs and displayed higher blood pressure in the clinic and at home. CONCLUSION: The worse clinical variables and relatively poorly controlled blood pressure of those with morning hypertension supports a potential relationship of morning hypertension with poor cardiovascular outcome. Morning blood pressure should be monitored at home for the optimal treatment of hypertension.
