Research progress of ectopic fat deposition in renal sinus affecting renal injury
10.3760/cma.j.cn441217-20231025-01040
- VernacularTitle:肾窦异位脂肪沉积对肾损伤影响的研究进展
- Author:
Shasha WANG
1
;
Jia HAN
;
Xiangyun LIU
Author Information
1. 上海健康医学院康复学院，上海201318
- Keywords:
Obesity;
Renal sinus;
Ectopic fat deposition;
Mechanical compression;
Lipotoxicity
- From:
Chinese Journal of Nephrology
2024;40(8):685-690
- CountryChina
- Language:Chinese
-
Abstract:
The increasing focus and research on ectopic fat deposition, especially the locally impactful liver and cardiac fat, have been extensively studied. However, there has been relatively less research on renal sinus fat. The increased ectopic deposition of renal sinus fat has an independent effect on renal damage, but the underlying mechanism remains unclear. Therefore, this article will integrate current research to provide a comprehensive review of renal sinus ectopic fat deposition, covering its related imaging diagnosis, potential mechanisms influencing renal damage (mechanical pressure generated by renal sinus fat, lipotoxicity), and current interventions for renal sinus ectopic fat deposition. This is aimed at attracting more attention in clinical research to the role of renal sinus ectopic fat deposition in the occurrence and development of kidney-related diseases.
