Hemophagocytic syndrome combined with thrombotic microangiopathy: a case report
10.3760/cma.j.cn441217-20231012-01015
- VernacularTitle:噬血细胞综合征合并血栓性微血管病1例
- Author:
Yan YANG
1
;
Yuqiu LIU
;
Bin WANG
;
Changsheng XU
;
Fengmei WANG
;
Xiaoliang ZHANG
;
Bicheng LIU
Author Information
1. 东南大学附属中大医院肾脏科，东南大学医学院，南京210009
- Keywords:
Lymphohistiocytosis, hemophagocytic;
Thrombotic microangiopathies;
Acute kidney injury
- From:
Chinese Journal of Nephrology
2024;40(7):558-561
- CountryChina
- Language:Chinese
-
Abstract:
The paper reports a rarely case of hemophagocytic syndrome complicated with thrombotic microangiopathy, first presented with fever of unknown origin. A 37-year-old female patient mainly presented with fever, hemolytic anemia, thrombocytopenia, and progressive decline in renal function. After infusion of fresh frozen plasma and high dose of glucocorticoid after double plasma exchange, the patient showed good prognosis, no further fever or hemolysis occurred, recovered platelet and renal function. After acute episode phase, kidney biopsy was performed and acute tubular necrosis was diagnosed. During the follow-up period, the disease did not recur, and the renal function was normal.
