A case of successful plasma exchange in the treatment of acute renal failure related to infective endocarditis
10.3760/cma.j.cn441217-20230912-00915
- VernacularTitle:血浆置换成功救治感染性心内膜炎相关急性肾衰竭1例
- Author:
Ying SUN
1
;
Haitao WANG
;
Fang FANG
;
Songlan WANG
;
Xin LIU
;
Yonghui MAO
Author Information
1. 北京医院肾内科 国家老年医学中心 中国医学科学院老年医学研究院，北京 100730
- Keywords:
Endocarditis, bacterial;
Acute kidney injury;
Plasma exchange
- From:
Chinese Journal of Nephrology
2024;40(6):484-486
- CountryChina
- Language:Chinese
-
Abstract:
A 65-year-old male was admitted because of anorexia, gross hematuria, skin purpura and acute renal insufficiency. Cardiovascular interventional examination was performed in other hospital 3 months before admission. During hospitalization, multiple blood cultures suggested positive Streptococcus gordonii, decreased blood complement and increased rheumatoid factor. Echocardiography revealed mitral valve vegetations (4 mm), and renal biopsy revealed endocapillary proliferative glomerulonephritis, diagnosed as infective endocarditis-associated glomerulonephritis. The combination of effective antibiotics and plasma exchange therapy significantly improved clinical symptoms and acute renal failure. The case suggests that plasma exchange is effective and safe in the treatment of immune complex-mediated glomerulonephritis caused by infective endocarditis, providing a new option for the treatment of such diseases.
