Lithium carbonate-induced distal renal tubular acidosis: a case report and literature review
10.3760/cma.j.cn441217-20230719-00708
- VernacularTitle:碳酸锂致远端肾小管酸中毒1例并文献复习
- Author:
Wenjun ZHANG
1
;
Xixi ZHENG
;
Wenling YE
;
Limeng CHEN
Author Information
1. 山西省阳泉市第一人民医院肾内科，阳泉 045000
- Keywords:
Lithium;
Acidosis, renal tubular;
Bipolar disorder;
Renal side effects
- From:
Chinese Journal of Nephrology
2024;40(5):389-391
- CountryChina
- Language:Chinese
-
Abstract:
Antipsychotics, lithium preparations can cause a variety of renal side effects, most of which occur insidiously. The paper reports a 46-year-old female patient developing fatigue and soft paresis after taking lithium carbonate for 17 years. Laboratory tests showed hypokalemia, distal renal tubular acidosis (dRTA), and renal calculus. After discontinuation of lithium carbonate, partial remission of hypokalemia and dRTA were observed. Combined with literature review, in addition to dRTA, the renal side effects of lithium preparations also include acute toxic kidney injury, nephrogenic diabetes insipidus and various glomerulopathy.
