Recent advance in early diagnosis and targeted intervention of cerebral small vascular disease
10.3760/cma.j.cn115354-20240626-00381
- VernacularTitle:脑小血管病早期诊断与靶向干预研究新进展
- Author:
Yuhan WANG
1
;
Yun XU
;
Qingxiu ZHANG
Author Information
1. 南京大学医学院附属鼓楼医院神经内科，南京 210008
- Keywords:
Cerebral small vessel disease;
Animal model;
Biomarker;
Therapeutics
- From:
Chinese Journal of Neuromedicine
2024;23(8):848-853
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral small vessel disease (CSVD) is a clinical condition resulting from lesions in the small blood vessels within the brain. Cause and mechanism of CSVD are intricate, and early diagnosis and specific treatment are currently lacking in clinical practice. This paper presents a synthesis of recent methodologies for creating animal models of CSVD, as well as a compilation of imaging and biological markers for CSVD early diagnosis. Additionally, the article reviews intervention strategies that target crucial pathways in the development of CSVD, aiming to offer novel insights into early diagnosis and intervention techniques for CSVD.
