Research progresses in imaging evaluation and treatment of branch atheromatous disease
10.3760/cma.j.cn113694-20240419-00280
- VernacularTitle:穿支动脉粥样硬化病的影像评估及治疗研究进展
- Author:
Cong GAO
1
;
Wenting LI
;
Xiaoling LIAO
Author Information
1. 首都医科大学附属北京天坛医院神经内科，北京 100070
- Keywords:
Branch atheromatous disease;
Imaging evaluation;
Treatment;
Early neurological deterioration
- From:
Chinese Journal of Neurology
2024;57(12):1382-1388
- CountryChina
- Language:Chinese
-
Abstract:
Branch atheromatous disease (BAD) is a common type of acute ischemic stroke, accounting for 10% to 15% of all ischemic stroke etiologies. Clinically, it often presents as early neurological deterioration (END) primarily characterized by progressive motor deficits, leading to poor clinical outcomes. The mechanism of END in BAD patients has not been fully elucidated, and there is a lack of effective risk prediction markers and treatment strategies. With the application of high-resolution and high-field magnetic resonance imaging technologies to evaluate the vessel wall of parent artery and the morphology of penetrating artery, the pathogenesis and progression mechanisms of BAD have been further revealed. Some studies have shown that the effectiveness and safety of using enhanced antiplatelet agents such as tirofiban or combining antiplatelet therapy with anticoagulant treatment such as argatroban are gradually emerging. This article will focus on the research progresses in imaging evaluation and treatment of BAD, aiming to enhance clinicians′ understanding of BAD to take early measures to prevent END, reduce recurrence, and improve patient prognosis.
