Current researches of the role of skull bone marrow in nervous system disease

VernacularTitle:颅骨骨髓在神经系统疾病中的作用研究
Author: Fanfan YE ¹ ; Yutao DU ; Guodong FENG
Author Information

1. 复旦大学附属中山医院神经内科，上海　200032
Keywords: Central nervous system diseases; Infection; Skull bone marrow; Immune cells
From: Chinese Journal of Neurology 2024;57(11):1274-1280
CountryChina
Language:Chinese
Abstract: The skull, surrounding the brain parenchyma, plays a role of protection and support. With the in-depth study of the interface of the central nervous system, ossified vascular channels connecting the dura and the skull bone marrow for cells traffic have been found, and the neuroimmune function of the skull has been gradually paid attention to. Here, this review will introduce the anatomy and immune function of the skull bone marrow, and then explore its changes during health and disease. It will further highlight the role of the skull bone marrow in neurological diseases such as stroke, glioblastoma, and neurodegenerative diseases.