Significance of subclinical seizures in focal epilepsy

VernacularTitle:亚临床发作在局灶性癫痫中的意义
Author: Chenmin HE ¹ ; Hongyi YE ; Lingli HU ; Shan WANG ; Shuang WANG
Author Information

1. 浙江大学医学院附属第二医院放射科，杭州310009
Keywords: Epilepsy; Electroencephalography; Subclinical seizures
From: Chinese Journal of Neurology 2024;57(9):1025-1030
CountryChina
Language:Chinese
Abstract: Subclinical seizures (SCS) are paroxysmal electroencephalogram (EEG) events that do not accompany obvious subjective or objective behavioral changes. They are not uncommon in EEG monitoring, with an intracranial EEG detection rate of about 50%-60%, significantly higher than the scalp EEG detection rate of about 10%. SCS most frequently occur in patients with temporal lobe epilepsy. In terms of EEG characteristics, SCS often remain confined to the epileptogenic zone but can also spread outside of it. Their value in localizing the epileptogenic zone is comparable to that of clinical seizures (CS). Additionally, the concordance between SCS and CS localization is associated with favorable surgical outcomes, indicating the significant value of SCS in focal epilepsy. A systematic review of domestic and international research on SCS is provided in this paper, aiming to enhance understanding in this area.