Neuroimaging advances in the regression of white matter hyperintensity of presumed vascular origin
10.3760/cma.j.cn113694-20240411-00230
- VernacularTitle:血管源性脑白质高信号消退的神经影像学研究进展
- Author:
Jinyi CAO
1
;
Weiyi ZHONG
;
Yunqing YING
;
Xin CHENG
Author Information
1. 复旦大学华山医院神经内科 国家神经疾病医学中心 国家老年疾病临床医学研究中心，上海 200040
- Keywords:
Cerebral small vessel diseases;
Neuroimaging;
Cognitive dysfunction;
White matter hyperintensity of presumed vascular origin;
Regression
- From:
Chinese Journal of Neurology
2024;57(8):907-914
- CountryChina
- Language:Chinese
-
Abstract:
As one of the imaging features of cerebral small vessel disease, white matter hyperintensity (WMH) of presumed vascular origin is quite common in the elderly. The burden of WMH is thought to progress slowly over time and is significantly associated with cognitive decline. However, the pathogenesis of WMH remains unclear and there is no effective treatment available. Recent studies have reported that some WMH lesions can regress during follow-up, along with progression and regression occurring alternately, suggesting that longitudinal changes in WMH are not unidirectional. This article presents a systematic review of current neuroimaging studies on WMH regression to enhance the understanding of dynamic changes in WMH and to provide new theoretical evidence for WMH intervention.
