Research progress on ideal cardiovascular health reducing risk of metabolic dysfunction-associated steatotic liver disease
10.3760/cma.j.cn114798-20240509-00439
- VernacularTitle:理想心血管健康与代谢功能障碍相关性脂肪性肝病关系的研究进展
- Author:
Xiaolan ZOU
1
;
Xiaoxiang XIE
;
Jinli RU
Author Information
1. 山西医科大学第二临床医学院，太原 030000
- Keywords:
Fatty liver;
Ideal cardiovascular health;
Ideal cardiovascular behavior;
Ideal cardiovascular factors
- From:
Chinese Journal of General Practitioners
2024;23(11):1216-1219
- CountryChina
- Language:Chinese
-
Abstract:
With the increasing prevalence of obesity and diabetes mellitus, the incidence rate of metabolic dysfunction-associated steatotic liver disease (MASLD) is on the rise. MASLD has become the most common chronic liver disease, affecting more than 30% of the global population and causing serious social and economic burden. Numerous studies have shown that the development of MASLD is associated with an increased risk of heart and blood vessel disease (CVD). In 2010, the American Heart Association proposed the concept of ideal cardiovascular health (ICH); in 2022, the scoring criteria were updated with the introduction of the Life′s Essential 8 (LE8), comprising 4 ideal cardiovascular behaviors (optimal diet, exercise, no smoking, mean sleep 7-9 h/d) and 4 ideal cardiovascular conditions (blood pressure<120/80 mmHg (1 mmHg=0.133 kPa) with no medication, no history of diabetes mellitus and fasting blood glucose<5.6 mmol/L or HbA1c<5.7%, non-high density lipoprotein cholesterol<3.36 mmol/L, body mass index<25 kg/m 2). It aims to provide clear, actionable goals for CVD prevention by providing a direct, simple way to quantify health behaviors. A growing number of studies also confirm that the higher level of LE8 metrics is closely associated with the lower risk of MASLD. This article reviews the latest research progress on ICH metrics for reducing risk of MASLD, in order to provide references for early and effective prevention and comprehensive management of MASLD patients.
