Risk factors for all-cause mortality of hypertensive patients in a community in Shanghai
10.3760/cma.j.cn114798-20240805-00662
- VernacularTitle:上海市某社区高血压患者全因死亡影响因素探讨
- Author:
Hongmei ZHANG
1
;
Ling CHEN
;
Yajuan WANG
;
Miao MIAO
;
Haiyan LENG
;
Tiemei RUAN
;
Xiaoying TANG
;
Lanping CAI
;
Yan WANG
;
Yu FENG
;
Puyang ZHENG
Author Information
1. 上海市闵行区莘庄社区卫生服务中心，上海 201199
- Keywords:
Hypertension;
Death;
Influencing factor
- From:
Chinese Journal of General Practitioners
2024;23(10):1037-1043
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors of all-cause death in hypertensive patients in the community.Methods:A cohort of 4 049 hypertensive patients who participated in annual health checkups at Xinzhuang Community Health Service Centre of Shanghai Minhang district from January to December 2012 were enrolled in the study. All-cause death was the endpoint event of this study, and patients were divided into a fatal group and a survival group. The collection date for the endpoint event was December 2022. A multivariate Cox regression model was used to analyse the independent risk factors of all-cause mortality among hypertensive patients in the community.Results:Among 4 049 patients aged (67.9±7.1) years, 1 856 (45.8%) were males. There were 610 cases in the fatal group and 3 439 cases in the survival group. Multivariate Cox proportional regression showed that male gender ( HR=1.446, 95% CI: 1.200-1.742, P<0.001), older age ( HR=1.130, 95% CI: 1.118-1.143, P<0.001), higher waist-to-height ratio ( HR=8.117, 95% CI: 2.235-29.481, P=0.001), positive urinary protein ( HR=2.974, 95% CI: 2.202-4.016, P<0.001), high fasting blood glucose ( HR=1.070, 95% CI: 1.012-1.131, P=0.017), and history of stroke ( HR=1.819, 95% CI: 1.414-2.340, P<0.001) were independent risk factors for all-cause mortality in hypertensive patients, while exercise≥1/week ( HR=0.816, 95% CI: 0.668-0.996, P=0.046) and taking lipid-lowering medications ( HR=0.459, 95% CI: 0.223-0.947, P=0.035) were protective factors for all-cause mortality. Conclusion:For hypertensive patients, male gender, older age, higher waist-to-height ratio, positive urinary protein, high fasting blood glucose, and history of stroke are risk factors for all-cause mortality, while exercise≥1/week and taking lipid-lowering medications are protective factors.
