Extraskeletal effects and related mechanisms of Vitamin D
10.3760/cma.j.cn114798-20231031-00340
- VernacularTitle:维生素D的骨外作用及相关机制进展
- Author:
Wendi YANG
1
;
Tian XU
;
Zhenlin ZHANG
;
Hua YUE
Author Information
1. 上海交通大学医学院附属第六人民医院骨质疏松和骨病专科，上海 200233
- Keywords:
Vitamin D;
Diabetes;
Cardiovascular diseases;
Immunoregulation;
Oncogenesis;
Sarcopenia
- From:
Chinese Journal of General Practitioners
2024;23(6):675-680
- CountryChina
- Language:Chinese
-
Abstract:
Vitamin D regulates calcium and phosphorus homeostasis, promotes bone growth, development and mineralization, therefore plays an important role in maintaining bone health. In recent years, the extraskeletal effects of vitamin D have received increasing attention with further research. Studies have shown that vitamin D is involved in the occurrence and development of various diseases, and vitamin D deficiency may lead to increased disease risk. However, there is still controversy over whether supplementing vitamin D brings definitely clinical benefits. This article reviews the extraskeletal effects and related mechanisms of vitamin D in obesity, diabetes, cardiovascular diseases, immunoregulation, oncogenesis and sarcopenia, providing information for further study on its biological activities and clinical applications.
