Wound immersion with weakly alkaline solution after debridement for refractory diabetic foot ulcer
10.3760/cma.j.cn114798-20230913-00156
- VernacularTitle:糖尿病足溃疡患者清创术后创面弱碱性溶液浸泡的治疗效果
- Author:
Zhen LIU
1
;
Lijie QIU
;
Jie ZHAO
;
Linjing ZHANG
;
Xuecheng SUN
;
Wenming LUO
Author Information
1. 潍坊市人民医院创伤骨科，潍坊261000
- Keywords:
Diabetic foot;
Chronic wound surface;
Weakly alkaline solution;
Efficacy
- From:
Chinese Journal of General Practitioners
2024;23(6):661-664
- CountryChina
- Language:Chinese
-
Abstract:
A total of 44 patients with diabetic foot ulcers were treated in the Traumatic Orthopedics Department of Weifang People′s Hospital from January 2019 to December 2022. After debridement of foot ulcers the wounds were soaked in alkaline water of pH 7.5-8.0 (study group, n=22) or covered with vaseline gauze following iodophor disinfection (control group, n=22). The therapeutic effects of the two methods were compared. Four weeks after debridement, the wound area of study group was smaller than that of control group (3.15 (0, 7.60) vs. 6.75 (3.50, 9.32)cm 2, P<0.05), and the proportion of positive wound bacterial culture was lower than that of control group (40.9% (9/22) vs. 72.7% (16/22), P<0.05). At 12 weeks after surgery, there was no statistically significant difference in the wound healing rate between the two groups (72.7% (16/22) vs. 63.6% (14/22)), but the healing time of the study group was significantly shorter than that of the control group ((6.56±2.68) vs. (9.50±3.87) weeks, P<0.05). It is suggested that immersion of weak alkaline solution is helpful to promote wound healing for patients with diabetic foot ulcers after debridement surgery.
