Research advances on treatment of recurrent IgA nephropathy after kidney transplantation
10.3760/cma.j.cn421203-20231208-00186
- VernacularTitle:肾移植术后IgA肾病复发的治疗进展
- Author:
Kewen CHEN
1
;
Jinghai LIU
;
Pei ZHANG
;
Junhao YU
;
Mingxing SUI
;
Li ZENG
Author Information
1. 海军军医大学第一附属医院器官移植中心，上海 200433
- Keywords:
Kidney transplantation;
IgA nephropathy;
Recurrence;
Steroid;
Immunosuppressants
- From:
Chinese Journal of Organ Transplantation
2024;45(9):636-640
- CountryChina
- Language:Chinese
-
Abstract:
IgA nephropathy (IgAN) is one common type of glomerulonephritis caused by a deposition of immune complexes in mesangium and partial capillary loops. It is also an important risk factor for end-stage renal disease (ESRD). Kidney transplantation (KT) has been an ultimate treatment for IgAN patients progressing into ESRD. However, there is still a high risk of recurrence after transplantation. Currently no effective treatment is available for recurrent IgAN. This review summarized the latest researches of managing IgAN recurrence after KT, such as optimal treatment, immunosuppression, complement therapy and surgery.
