Advances in mesenchymal stem cell-derived exosome for tissue regeneration in cardiothoracic surgery
10.3760/cma.j.cn421203-20231019-00134
- VernacularTitle:间充质干细胞衍生的外泌体促进组织再生在心胸外科领域的研究进展
- Author:
Haoxin WAN
1
;
Tian XIA
;
Ziqing SHEN
;
Shu PAN
;
Cheng DING
;
Jun ZHAO
Author Information
1. 苏州大学附属第一医院胸外科,苏州 215006
- Keywords:
Mesenchymal stem cell;
Exosome;
Tissue regeneration
- From:
Chinese Journal of Organ Transplantation
2024;45(8):558-563
- CountryChina
- Language:Chinese
-
Abstract:
With continuous developments of regenerative medicine, mesenchymal stem cell-derived exosome (MSC-Exo) has attracted a growing attention of researchers with their inherent advantages of promoting tissue regeneration, an excellent biocompatibility and a great ease of penetration into tissues. Its specific mechanism has become a research hotspot. In cardiothoracic surgery, the role of MSC-Exo has been gradually examined. Currently the relevant studies have been conducted in the fields of cardiology, ung disease, lung transplant, tracheal transplantation and esophageal repair. The latest researches on MSC-Exo in the field of cardiothoracic surgery as well as its mechanism and outcomes were systematically summarized to provide references for more related researches in the future.