COVID-19 infection secondary to pulmonary mucormycosis in a recipient of simultaneous pancreas-kidney transplantation: one case report
10.3760/cma.j.cn421203-20230716-00027
- VernacularTitle:胰肾联合移植受者新型冠状病毒感染继发肺毛霉菌病1例
- Author:
Rongxin CHEN
1
;
Jiali FANG
;
Guanghui LI
;
Luhao LIU
;
Jialing WU
;
Zebin GUO
;
Zheng CHEN
Author Information
1. 广州医科大学附属第二医院器官移植科，广州 510260
- Keywords:
Simultaneous pancreas and kidney transplantation;
Pulmonary mucormycosis;
COVID-19
- From:
Chinese Journal of Organ Transplantation
2024;45(6):408-411
- CountryChina
- Language:Chinese
-
Abstract:
One case of COVID-19 infection secondary to pulmonary mucormycosis in a recipient of simultaneous pancreas-kidney transplantation was described. Early identification of the pathogen was achieved by metagenomic next-generation sequencing. On the basis of disease status and liver function changes, targeted treatments included intravenous amphotericin B liposome, amphotericin B nebulization& gargling and subsequently a maintenance therapy of oral posaconazole. This regimen resulted in the absorption of lung infection, stabilization of transplanted pancreas function and reduced levels of creatinine and urea as compared to pre-infection period. The therapeutic efficacy was decent.
