New advances in diagnostic and therapeutic strategies for invasive fungal disease in organ transplant recipients
10.3760/cma.j.cn421203-20231026-00142
- VernacularTitle:器官移植受者侵袭性真菌病的诊疗策略新进展
- Author:
Chunrong JU
1
;
Tongyi MEN
;
Wujun XUE
Author Information
1. 广州医科大学附属第一医院器官移植科（呼吸与危重症科）广州呼吸健康研究院国家呼吸医学中心 国家呼吸系统疾病临床医学研究中心 呼吸疾病国家重点实验室，广州 310003
- Keywords:
Organ transplantation;
Invasive fungal disease;
Antifungal medication;
Immunosuppressant
- From:
Chinese Journal of Organ Transplantation
2024;45(4):233-242
- CountryChina
- Language:Chinese
-
Abstract:
Long-term use of immunosuppressants result in an immunocompromised state, repeated hospitalizations and dosing of broad-spectrum antibiotics. Presence of transplant-associated diabetes and cadaveric donations are contributing factors to a higher risk of invasive fungal disease (IFD ) among solid organ transplantation (SOT) recipients. Furthermore, the epidemiology of IFD in SOT recipients has continuously evolved in recent years. Understanding the current epidemiological status of IFD in SOT recipients, becoming familiar with new diagnostic technologies for IFD and mastering the characteristics of novel antifungal medications may further improve the prognosis for recipients. This review summarized the incidence, pathogen composition, new diagnostic technologies and recently marketed novel antifungal medications for IFD in SOT recipients, aiming to offer references for clinical practices.
