Eliminating de novo donor specific antibodies with immunoadsorption for improving platelet engraftment after allogeneic hematopoietic stem cell transplantation: one case report
10.3760/cma.j.cn421203-20231008-00121
- VernacularTitle:应用蛋白A免疫吸附技术清除造血干细胞移植后新生供体特异性抗体促进血小板植入的再生障碍性贫血1例
- Author:
Ling LI
1
;
Jing LI
;
Qian ZHU
;
Shiyuan ZHOU
;
Chao MA
;
Shijia LI
;
Xiao MA
;
Jun HE
;
Depei WU
;
Xiaojin WU
Author Information
1. 苏州大学附属第一医院血液内科，国家血液系统疾病临床医学研究中心，江苏省血液研究所，苏州大学造血干细胞移植研究所，苏州 215006
- Keywords:
Aplastic anemia;
Immunoadsorption;
Haploidentical hematopoietic stem cell transplantation;
Donor specific antibody
- From:
Chinese Journal of Organ Transplantation
2024;45(3):184-187
- CountryChina
- Language:Chinese
-
Abstract:
To explore the efficacy and safety of immunoadsorption (IA) in removing de novo donor specific antibody (DSA) after allogeneic hematopoietic stem cell transplantation (HSCT), the relevant clinical data were retrospectively reviewed for one female patient of severe aplastic anemia (SAA). Desensitization treatment with IA after HSCT was offered for removing de novo DSA and ultimately promoting platelet engraftment at First Affiliated Hospital of Soochow University in March 2021.
