A short term result of paclitaxel-coated balloon angioplasty versus common balloon angioplasty for below-the-ankle artery sclerosis obliterans
10.3760/cma.j.cn113855-20231007-00217
- VernacularTitle:踝下动脉球囊成形术中紫杉醇药涂球囊与普通球囊疗效对比
- Author:
Zhijuan LI
1
;
Tiantian LI
;
Baixi ZHUANG
;
Xueyuan ZHANG
;
Yujie WANG
;
Xuan ZHANG
;
Miao YANG
Author Information
1. 中国中医科学院西苑医院周围血管科，北京 100091
- Keywords:
Atherosclerosis obliteran;
Angioplasty,balloon;
Chronic limb-threatening ischemia;
Below-the-ankle artery lesion
- From:
Chinese Journal of General Surgery
2024;39(11):855-860
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the short-term efficacy of drug-coated balloon and common balloon in the treatment of with below-the-ankle arteriosclerosis obliterans (ASO).Methods:The clinical and follow-up data of 115 patients (118 limbs) with lower extremity ASO of Rutherford 4-6 admitted to the Department of Peripheral Vascular Diseases, Xiyuan Hospital, China Academy of Chinese Medical Sciences from Jun 2021 to Jun 2023 were retrospectively analyzed.Results:Patients were divided into group of 52 limbs using paclitaxel-coated balloon and group of 66 limbs using common balloon. During the 6-month follow-up period, The total effective rate of wound surface was 98.1% in the drug-coated balloon group and 92.4% in the common balloon group. The difference was statistically significant ( P<0.05); the increase of ankle-brachial index (ABI) and toe-brachial index (TBI) in the drug-coated balloon group were significantly better than common balloon group, and the difference was statistically significant ( P<0.01). No major adverse events occurred in the two groups during the 6-month follow-up period. Compared with the common balloon group, the drug-coated balloon group had a higher limb salvage rate (100.0% vs. 98.5% ) and a lower target vessel reconstruction rate (7.7% vs.18.2%), though the difference was not statistically significant ( P>0.05). Conclusion:Compared with the common balloon, the drug-coated balloon is more effective in the treatment of patients with wound healing rate and vascular patency rate in Rutherford 4-6 grade below-the-ankle artery lesions.
