Practice of enhanced recovery after surgery reduces postoperative inflammation in patients undergoing laparoscopic gastric cancer surgery
10.3760/cma.j.cn113855-20230920-00172
- VernacularTitle:加速康复外科减轻腹腔镜胃癌手术患者术后炎症反应
- Author:
Jingyi WANG
1
;
Jun ZHONG
;
Chaogang YANG
;
Xiaojiao WANG
;
Meng WEI
;
Xiaoyan CHEN
;
Bilong FENG
;
Chunwei PENG
Author Information
1. 武汉大学中南医院胃肠外科，武汉 430071
- Keywords:
Rehabilitation research;
Stomach neoplasms;
Laparoscopic surgery;
Systemic inflammatory response syndrome
- From:
Chinese Journal of General Surgery
2024;39(11):833-838
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the application of enhanced recovery after surgery in patients undergoing laparoscopic gastric cancer surgery and its impact on the systemic inflammatory response (SIR).Methods:The clinical data of patients undergoing laparoscopic gastric cancer surgery at the Department of Gastrointestinal Surgery, Zhongnan Hospital, Wuhan University from Mar 2021 to Mar 2023 was retrospectively analyzed.Results:A total of 234 patients with gastric cancer were enrolled (120 cases in ERAS group and 114 cases in routine group). There were no significant differences in preoperative indexes between the two groups (all P>0.05). After laparoscopic surgery, the postoperative ventilation time and hospital stay of patients in ERAS group were significantly shorter than those in the conventional group (all P<0.05). Neutrophil to lymphocyte ratio (NLR) , platelet to lymphocyte ratio (PLR) and systemic immune-inflammatory (SII) index of patients in ERAS group were significantly lower on day 1 and day 3 after surgery than in conventional group (all P<0.05). The ratio of lymphocyte to monocyte (LMR) in ERAS group was significantly higher than that in conventional group on day 1 and day 7 after surgery (all P<0.05). Conclusions:ERAS can improve postoperative SIR indexes in patients undergoing laparoscopic gastric cancer surgery, shorten postoperative recovery time, and enhance the efficacy of laparoscopic gastric cancer surgery by reducing perioperative systemic inflammation.
