A national multi-center prospective study on the perioperative practice of enhanced recovery after surgery for choledochal cysts in children
10.3760/cma.j.cn113855-20240426-00309
- VernacularTitle:加速康复外科在小儿胆总管囊肿围手术期应用的全国多中心前瞻性研究
- Author:
Ming YUE
1
;
Jiexiong FENG
;
Yan′an LI
;
Yuanmei LIU
;
Zhigang GAO
;
Qi CHEN
;
Hongwei XI
;
Qiang YIN
;
Chengji ZHAO
;
Yuzuo BAI
;
Wanfu LI
;
Libin ZHU
;
Weibing TANG
;
Hongqiang BIAN
;
Huizhong NIU
;
Zhiheng GUO
;
Heying YANG
Author Information
1. 郑州大学第一附属医院小儿外科，郑州 450052
- Keywords:
Rehabilitation research;
Choledochal cyst;
Perioperative Period;
Stress response
- From:
Chinese Journal of General Surgery
2024;39(11):827-832
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and efficacy of enhanced recovery after surgery(ERAS) in the perioperative period of congenital choledochal cysts in children.Methods:This is a multicenter prospective randomized controlled study. The clinical data of 273 pediatric congenital choledochal cysts(CCC) patients who underwent surgery at 14 medical centers with complete follow-up data were collected through the medical data analysis platform. Among them, 123 cases in ERAS group were managed perioperatively in strict accordance with ERAS mode, and 150 cases in conventional group were managed according to traditional mode. The length of hospital stay,time to first farting, time to complete feeding, the incidence of complications, cost and readmission rate within 30 days,stress indexes and liver function were compared between the two groups.Results:Compared with the conventional group, median time to start farting (2.0 d vs. 3.0 d, P<0.001), median time to complete feeding (5.0 d vs. 7.0 d, P<0.001), median postoperative hospitalization time (6.0 d vs. 9.0 d, P<0.001),the median total length of stay(13.0 d vs. 15.0 d, P<0.001) were shorter,the median hospitalization cost (37,000 yuan vs.43,000 yuan P<0.001) was lower, and stress indexes recovered quickly. The incidence of postoperative hospital stay and readimission rate within 30 d were not statistically different between the two groups. Conclusion:It is safe and feasible to implement ERAS for children with CCC in the perioperative period, which can reduce stress response, speed up recovery,and save medical costs.
