The value of parathyroid autotransplantation in endoscopic radical operation for thyroid carcinoma
10.3760/cma.j.cn113855-20230825-00081
- VernacularTitle:甲状旁腺自体移植术在腔镜甲状腺癌根治术中的临床应用价值
- Author:
Qi ZHANG
1
;
Tingbao CAO
;
Yupeng ZHANG
;
An SUN
;
Runhong WANG
;
Tongying YI
;
Kunpeng QU
Author Information
1. 甘肃省中心医院普外三科，兰州 730000
- Keywords:
Thyroid neoplasms;
Organ transplantation;
Hypoparathyroidism;
Lymph node excision
- From:
Chinese Journal of General Surgery
2024;39(8):598-603
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of parathyroid autotransplantation on total central lymph node dissection and postoperative parathyroid functional recovery in endoscopic radical operation for thyroid carcinoma.Method:The data of 152 patients undergoing endoscopic radical operation for thyroid carcinoma are retrospectively analyzed. The incidence of postoperative hypoparathyroidism, serum PTH and Ca 2+ concentrations at different time points, and the number of lymph nodes cleared were counted. Results:The rate of temporary hypoparathyroidism in the experimental group was higher than that in the control group, and the incidence of permanent hypoparathyroidism was lower than that in the control group, with statistically significant differences ( χ2=6.243, P=0.029). Patient's PTH in the experimental group is significantly higher than that in the control group at 1 week, 1 , 3 , 6 and 12 months after operation, and the difference is statistically significant ( F=25.193, P<0.05); Ca 2+ concentration in experimental group is higher than that in control group at 1, 3, 6 and 12 months after operation, and the difference is statistically significant ( F=3.268, P=0.005); The average number of central zone lymph node dissection and positive lymph nodes per case in the experimental group was higher than that in the control group, and the difference was statistically significant ( t=2.000, P=0.047; t=2.014, P=0.046). Conclusion:In radical lumpectomy for thyroid cancer, parathyroid autotransplantation can effectively prevent permanent postoperative hypoparathyroidism while achieving a more complete lymph node dissection in the central region.
