A Case of Anti-Jk(a) Whose Reactivity Was Abolished in an Enzyme Gel Test.
- Author:
Jeong Won SHIN
1
;
Gum Ran CHAI
;
Hae In BANG
;
Rojin PARK
;
Tae Youn CHOI
Author Information
1. Department of Laboratory Medicine, Soonchunhyang University Hospital, Seoul, Korea. jwshin@hosp.sch.ac.kr
- Publication Type:Case Report
- Keywords:
Anti-Jk(a);
LISS/Coombs gel card;
Enzyme gel card
- MeSH:
Catheters;
Drainage;
Female;
Fever;
Humans;
Liver Abscess;
Mass Screening;
Middle Aged;
Nausea;
Phenotype;
Vomiting
- From:Korean Journal of Blood Transfusion
2009;20(2):134-137
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of Anti-Jk(a), whose reactivity was abolished in an enzyme gel test. A 56-year-old woman was admitted to our hospital because of fever, myalgia, nausea and vomiting. Anti-Jk(a) was detected by antibody screening and an identification test using a LISS/Coombs gel card (DiaMed AG, Cressier sur Morat, Switzwerland). Its reactivity was so weak (trace ~ 1+) that an Enzyme gel card (DiaMed AG) was added to enhance the reactivity. Unexpectedly, all reactions with the enzyme-treated cells showed negative results. The patient's RBC phenotype was Jk(a-b+). The abdominal CT revealed a 6x7.5 cm sized liver abscess. Her condition improved after percutaneous catheter drainage and she was discharged on the 23rd hospital day.