A Case of Simultaneously Detecting Anti-D as an Autoimmune Antibody and Anti-E as an Alloimmune Antibody.
- Author:
Min Gu KANG
1
;
Young Ae LIM
;
Kyoung Un PARK
Author Information
1. Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea. limyoung@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Anti-D;
Anti-E;
RhD;
Autoimmune antibody;
Alloimmue antibody
- MeSH:
Aged;
Anemia, Hemolytic, Autoimmune;
Coombs Test;
Erythrocytes;
Female;
Humans;
Immunoglobulin G;
Isoantibodies;
Phenotype;
Spine;
Spondylitis
- From:Korean Journal of Blood Transfusion
2009;20(2):138-143
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report here on a case of simultaneously detecting anti-D as an autoimmune antibody and anti-E as an alloimmune antibody without any evidence of autoimmune hemolytic anemia. A 66-year-old female with tuberculous spondylitis was admitted for removing a previously-placed surgical screw in her spine. She had received antituberculosis drugs and six units of AB, RhD positive packed red blood cells during the previous 6 months. The laboratory findings were as followings: the direct antiglobulin test was positive for IgG, the Rh phenotype of the erythrocytes was typed as group CcDe and RhD antigen was confirmed by the molecular method and the serological method to rule out partial-D.
