Dermabrasion for the treatment of familial benign chronic pemphigus: a clinical observation of 6 cases
- VernacularTitle:皮肤磨削术治疗家族性良性慢性天疱疮6例临床观察
- Author:
Yuqing SONG
1
;
Nan YANG
;
Linlin LIU
;
Ziyi FENG
;
Shixin HAN
;
Meijuan ZHOU
Author Information
- Keywords: Pemphigus, benign familial; Dermabrasion; Surgical procedures, operative; Pathologic processes; Recurrence; Treatment outcome
- From: Chinese Journal of Dermatology 2024;57(8):743-746
- CountryChina
- Language:Chinese
- Abstract: Objective:To analyze clinical efficacy and safety of dermabrasion for the treatment of familial benign chronic pemphigus.Methods:Clinical data were retrospectively collected from 6 patients with familial benign chronic pemphigus, who underwent dermabrasion in the Department of Dermatology, the First Affiliated Hospital of Dalian Medical University from February 2019 to July 2020. There were 3 males and 3 females, they were aged from 39 to 65 years, and their disease duration ranged from 10 to 40 years. All the patients were postoperatively followed up for 14 - 34 months. Response rates were calculated, and adverse reactions and recurrence were observed.Results:Dermabrasion was performed on the 6 patients in 55 body areas. After operation, complete recovery was observed in 36 areas (65.5%), marked improvement was noted in 13 areas (23.6%), and moderate improvement was observed in 6 areas (10.9%) ; there were no areas with no response, resulting in an overall response rate of 89.1%. Postoperatively, the patients experienced no obvious discomfort, and only slight hypopigmentation and mild scars remained. During the follow-up of 14 to 34 months, no recurrence was observed in the treated areas.Conclusion:Dermabrasion was safe and effective for the treatment of familial benign chronic pemphigus.
