Port-wine stains: mechanisms underlying the development and progression
- VernacularTitle:鲜红斑痣发病及进展机制研究进展
- Author:
Haotian CHEN
1
;
Lian LIU
;
Ting ZHANG
;
Qingfeng LIU
;
Xiaoxue LI
;
Ping DIAO
;
Xian JIANG
Author Information
- Keywords: Port-wine stain; Vascular malformations; Therapy; Pathogenesis; Disease progression
- From: Chinese Journal of Dermatology 2024;57(7):661-664
- CountryChina
- Language:Chinese
- Abstract: Port-wine stains (PWS) are vascular malformations characterized by dilated capillaries and postcapillary venules in the skin. Clinically, they mainly manifest as pink or red irregular patches, most of which may become thickened, darkened in color, or even develop into nodules over age, making treatment more challenging. The mechanisms underlying the development and progression of PWS are not very clear, and may be related to heredity, gene mutations, abnormal ratios of blood vessels to nerves, etc. This review summarizes research progress in the mechanisms underlying the development and progression of PWS, so as to provide a theoretical basis for their treatment.
