Clinical effects of Zhenwu Decoction combined with Danshen Drink on patients with chronic heart failure
10.3969/j.issn.1001-1528.2024.11.017
- VernacularTitle:真武汤联合丹参饮对慢性心力衰竭患者的临床疗效
- Author:
Xiao-Sheng MA
1
;
Di ZHANG
;
Jing MA
;
Chun-Xu XING
;
Guang CHEN
Author Information
1. 牡丹江医学院附属第二医院心内科,黑龙江 牡丹江 157000
- Keywords:
Zhenwu Decoction;
Danshen Drink;
conventional treatment;
chronic heart failure
- From:
Chinese Traditional Patent Medicine
2024;46(11):3651-3654
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Zhenwu Decoction combined with Danshen Drink on patients with chronic heart failure.METHODS Eighty-six patients were randomly assigned into control group(43 cases)for 4-week intervention of conventional treatment,and observation group(43 cases)for 4-week intervention of Zhenwu Decoction,Danshen Drink and conventional treatment.The changes in cardiac function indices(LVFS,LVEDD,LVEF),serum indices(hs-cTnI,sST2,NT-proBNP,MMP-9),inflammatory factors(IL-6,TNF-α,hs-CRP),platelet aggregation rate,QTcd and incidence of adverse reactions were detected.RESULTS After the treatment,the two groups demonstrated increased LVFS,LVEF(P＜0.05),and decreased LVEDD,serum indices,inflammatory factors,platelet aggregation rate,QTcd(P＜0.05),especially for the observation group(P＜0.05).No significant difference in incidence of adverse reactions was found between the two groups(P＞0.05).CONCLUSION For the patients with chronic heart failure,Zhenwu Decoction combined with Danshen Drink can safely and effectively improve hs-cTnI level and platelet aggregation functions.
