Clinical effects of Xuanfei Jiejing Decoction combined with conventional treatment on patients with asthma of Wind-Phlegm Obstructing Lung Pattern
10.3969/j.issn.1001-1528.2024.11.014
- VernacularTitle:宣肺解痉方联合常规治疗对风痰阻肺型哮喘患者的临床疗效
- Author:
Yun GUAN
1
;
Lei WU
;
Xuan ZHANG
;
Ming-Ming DUAN
;
Fei-Fei PENG
Author Information
1. 河北省中医院呼吸重症科,河北 石家庄 050013
- Keywords:
Xuanfei Jiejing Decoction;
conventional treatment;
asthma;
Wind-Phlegm Obstructing Lung
- From:
Chinese Traditional Patent Medicine
2024;46(11):3636-3640
- CountryChina
- Language:Chinese
-
Abstract:
AIM To investigate the clinical effects of Xuanfei Jiejing Decoction combined with conventional treatment on patients with asthma of Wind-Phlegm Obstructing Lung Pattern.METHODS One hundred and fifty patients were randomly assigned into control group(75 cases)for 4-week intervention of conventional treatment,and observation group(75 cases)for 4-week intervention of both Xuanfei Jieshi Decoction and conventional treatment.The changes in clinical effects,TCM syndrome scores,airway inflammatory indices(ECP,IL-4,IgE),lung function indices(FVC,FEV1/FVC,PEF)and putum and mucus indices(4 h sputum volume,sputum viscosity,mucin 5AC)were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P＜0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,airway inflammatory indices,putum and mucus indices(P＜0.05),and increased lung function indices(P＜0.05),especially for the observation group(P＜0.05).CONCLUSION For the patients with asthma of Wind-Phlegm Obstructing Lung Pattern,Xuanfei Jiejing Decoction combined with conventional treatment can reduce airway inflammatory levels,inhibit airway mucus secretion,improve lung functions,and alleviate clinical symptoms.
